Table 3

Associations between immunohistochemical expression, histology and tumor size
Histological subtype Tumor size
ADC (n = 123) SCC (n = 49) LCC (n = 24) p value* ≤ 3.0 cm (n = 1 9) ≥ 3.1 cm (n = 87) p value*
S100A4c negative/weak 34% 57% 58% 36% 51%
moderate 37% 37% 38% 38% 36%
strong 29% 6% 4% 0.001 26% 13% 0.01
S100A4n negative 13% 33% 29% 18% 22%
weak 32% 34% 38% 29% 40%
moderate 26% 27% 29% 27% 25%
strong 29% 6% 4% 0.001 26% 13% 0.04
Ephrin-A1 negative 11% 29% 4% 15% 14%
moderate 71% 65% 92% 70% 75%
strong 18% 6% 4% 0.004 15% 11% 0.79
Osteopontin negative 23% 21% 25% 26% 20%
moderate 67% 61% 66% 62% 69%
strong 10% 18% 9% 0.61 12% 11% 0.54

* p value calculated by Fisher´s exact test or linear by linear association test as appropriate.

Rud et al.

Rud et al. BMC Cancer 2012 12:333   doi:10.1186/1471-2407-12-333

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