Table 1

Association of demographic and clinico-pathological characteristics with expression levels of Bax, Bcl-2 and Bcl-XL
N=69 Univariate Analysis Baxa n=64 Bcl-2a n=63 Bcl-XLa n=63
# OF CASES (%) Hazard Ratio 95% CI p-value Low High p-value Low High p-value Low High p-value
GENDER 1.72 0.693 - 4.286 0.24 0.419 0.109 0.419
Male 49 71.01 20 24 18 25 20 23
Female 20 28.99 12 8 13 7 12 8
AGEb 1.35 0.543 - 3.364 0.52 1.000 0.315 0.616
<60 years 29 42.03 15 14 12 17 16 13
≥60 years 40 57.97 17 18 19 15 16 18
pT STATUS 2.55 1.022 - 6.357 0.05 0.616 0.207 0.616
1 + 2 38 55.07 19 16 20 15 19 16
3 + 4 31 44.93 13 16 11 17 13 15
pN STATUS 7.470 2.467 - 22.611 <0.0001 0.315 0.802 1.000
N0 39 56.52 15 20 16 18 17 17
N1 + N2 30 43.48 17 12 15 14 15 14
SMOKING HISTORY 0.65 0.245 - 1.702 0.38 0.075 0.148 0.237
Never 15 21.74 11 4 10 5 10 5
Ever 54 78.26 21 28 21 27 22 26
ALCOHOL HISTORY 0.46 0.162 - 1.282 0.14 1.000 1.000 1.000
Never 11 17.46 5 4 4 5 5 4
Ever 52 82.54 27 23 23 26 24 24
TUMOUR DIFFERENTIATION 1.62 0.772 - 3.427 0.2 1.000 0.923 0.525
Well 14 22.95 7 6 6 7 8 5
Moderate 38 62.30 18 18 19 16 15 20
Poor 9 14.75 4 3 4 3 3 4
TREATMENT 2.16 0.629 - 7.412 0.22 0.257 0.011 0.164
Surgery 18 26.09 6 11 13 4 6 11
Surgery + RXT 51 73.91 26 21 18 28 26 20
STAGE 4.68 1.358 - 16.087 0.01 1.000 0.797 1.000
I + II 26 37.68 11 12 12 11 12 11
III + IV 43 62.32 21 20 19 21 20 20
PROLIFERATION (Ki67) 0.6 0.231 - 1.539 0.29 0.001 0.617 0.211
Low 32 50.00 23 9 17 15 19 13
High 32 50.00 9 23 14 17 13 18

aCut-point selected at median.

bMedian value.

Bose et al.

Bose et al. BMC Cancer 2012 12:332   doi:10.1186/1471-2407-12-332

Open Data