Table 4

Details of surgery and surgical complications
Details of surgical resections Peri-operative chemotherapy Surgery alone Total cohort
n = 56 resections (38 patients) n = 16 resections (13 patients) n = 72 resections (51 patients)
Type of resection
 Wedge 37 10 47
 Segmental 8 2 10
 Lobectomy 8 4 12
 Pneumonectomy 1 0 1
 Not recorded 2 0 2
Metastases removed
 Solitary 16 4 20
 Multiple 38 12 50
 Unknown 2 0 2
Median size (range) 14.5 mm (2–60) 15 mm (4–25) 15 mm (2–60)
Lymph node dissection
 Yes 22 5 27
Positive histology 4/22 (18%) 1/5 (20%) 5/27 (19%)
 No 31 10 41
 Unknown 3 1 4
Time from last dose of neoadjuvant treatment to surgery Median days (range)
 Any treatment 48.5 (14–207)
 Chemotherapy + 37 (25–85)
 VEGF inhibitor
Surgical Complications* 3/68 (4%) 5/16 (31%) 8/84 (9%)
 Prolonged air leak 3 0 3
 Haemorrhage** 0 1 1
 CVA 0 1 1
 Cardiac Arrhythmia (fast AF) 0 1 1
 Small bowel ileus or obstruction 0 2 2

Numbers in table refer to number of resections unless otherwise specified.

*Surgical complications were evaluated in all operations performed, hence the bilateral sequential resections being counted as separate events and the total n = 86, not 72.

**The patient was fully anticoagulated.

CRC colorectal cancer, CRT chemoradiation, RT radiotherapy, CEA carcinoembryonic antigen, ULN upper limit of normal, VEGF vascular endothelial growth factor, CVA cerebrovascular Accident, AF atrial Fibrillation.

Hawkes et al.

Hawkes et al. BMC Cancer 2012 12:326   doi:10.1186/1471-2407-12-326

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