Table 2

Concordance between radiology, PET and histology
PET positive PET negative No PET done
n (%) n (%) n (%)
Patients* 39 (81) 8 (18) 6 (12)
Resections 48 (86) 8 (14) 16 (22)
Timing of pre-thoracotomy PET
Before neoadjuvant chemotherapy 16 3 -
After neoadjuvant chemotherapy 12 1 -
No neoadjuvant chemotherapy 20 4 -
CT identified metastases
Median number (range) 1 (1–6) 2 (1–3) 2 (1–11)
PET identified metastases
Median number FDG avid (range) 1(1–6) - -
Histologically identified metastases#
Median number (range) 1 (1–6) 2 (1–4) 1 (1–12)
Median size of largest nodule (range) 15 mm (5–60) 8 mm (3–15) 15 mm (2–25)
Concordance rates on number of metastases+
CT + PET 34 (71) - -
CT + Histology 28 (61) 4 (50) 10 (71)
PET + Histology 33 (72) - -
CT + PET + Histology 26 (57) - -

*2 patients had FDG-avid lung lesions prior to one lung resection but no FDG avid lung lesions prior to a subsequent lung resection.

#Histology obtained at time of resection. All lesions considered involved had viable tumour.

+histology not available on 1 PET positive patient, and 2 patients who did not have a PET.

Hawkes et al.

Hawkes et al. BMC Cancer 2012 12:326   doi:10.1186/1471-2407-12-326

Open Data