Table 4

Association between brain response and systemic response in patients with brain metastasis at study entry
Best Systemic Response Best Brain Response
CR PR Any response SD > 6 m SD < 6 m PD Total P-value*
No (%) No (%) No (%) No (%) No (%) No (%) No (%)
CR 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0.0001
PR 1 (50.0) 2 (33.3) 12 (60.0) 2 (25.0) 0 (0.0) 1 (14.3) 18 (38.3)
SD > 6 m 0 (0.0) 0 (0.0) 3 (15.0) 6 (75.0) 1 (25.0) 0 (0.0) 10 (21.3)
SD < 6 m 1 (50.0) 4 (66.7) 3 (15.0) 0 (0.0) 3 (75.0) 2 (28.6) 13 (27.7)
PD 0 (0.0) 0 (0.0) 2 (10.0) 0 (0.0) 0 (0.0) 4 (57.1) 6 (12.8)
Total 2 (3.7) 6 (11.1) 20 (37.0) 8 (14.8) 4 (7.4) 7 (13.0) 47 (100.0)

* The patients with evaluable response were calculated by Fisher’s exact test.

CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease.

Ro et al.

Ro et al. BMC Cancer 2012 12:322   doi:10.1186/1471-2407-12-322

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