Table 2

Chromosome imbalance regions with different alteration frequency in relation to tumor subtypes in lung cancer
Chromosome Cytoband Start site End site Size (Mb) BAC number ADCa (n=20) SCCa (n=20) Difference in alteration frequency
A. Asian
2 p24.1 20863719 22199349 1.30 10 Loss :85% Loss :30% 55%
3 p25.2-25.3 9867502 12488641 2.60 18 Loss :25% Gain :40% 65%
6 p22.1 28165236 28452189 0.30 6 Gain :85% Gain :25% 60%
10 q22.3 77428562 79105320 1.70 17 Gain :15% Loss :45% 60%
10 q24.1 98845671 99207113 0.36 4 Gain :50% Gain :70% 20%
17 p13.1 7918593 7993947 0.10 2 Loss :10% Gain :45% 55%
17 q24.2 62769444 63340772 0.60 5 Loss :60% 0 60%
B. Caucasian
2 p23.3 23804032 26257119 2.45 17 Gain :60% 0 60%
3 p11.2-12.1 85893658 87649703 1.76 14 Loss :100% Loss :40% 60%
3 p14.2-14.3 56804094 61897044 5.09 33 Gain :20% Gain :80% 60%
3 p22.2-24.1 29648645 38540543 8.89 25 Loss :70% 0 70%
4 p15.2-15.3 21407638 23952439 2.54 27 0 Loss :80% 80%
6 p12.3 47804985 47961964 0.16 2 0 Gain :60% 60%
6 p22.1-22.2 25985490 26318093 0.33 5 0 Gain :50% 50%
6 q21.1 73325343 73596310 0.27 2 Loss :60% 0 60%
9 q22.2-22.3 76902029 78697046 1.80 17 Loss :50% Gain :20% 70%
10 q21.2 74105644 74697200 0.59 6 0 Gain :60% 60%
12 p13.3 8010296 9309215 1.30 11 Loss :90% Loss :10% 80%
12 q24.2 63460935 64329625 0.87 14 Loss :10% Loss :60% 50%
17 p22.2 15476489 15931167 0.45 4 Gain :60% 0 60%
X q21.3 87836131 89896378 2.06 17 0 Gain :60% 60%

aADC: adenocarcinoma; SCC: squamous cell carcinoma.

Lo et al.

Lo et al. BMC Cancer 2012 12:235   doi:10.1186/1471-2407-12-235

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