Table 3

Advantages and disadvantages of deferring treatment in asymptomatic FL patients (watchful waiting)
Advantages
· Patients are spared the effects of acute toxicity
· Patients are spared the effects of serious late toxicity (i.e., myelodysplasia)
· The development of shared "cross-resistance" to other therapies is avoided
Disdvantages
· Risk of severe complications associated with the disease during the interval between visits
· The chances of obtaining a good antitumor response with the first course of treatment can decrease [16]
· The risk of FL transformation into aggressive lymphoma can increase [23]
· Anxiety caused by the fact of suffering an oncologic disease that is not being treated

Rueda et al.

Rueda et al. BMC Cancer 2012 12:210   doi:10.1186/1471-2407-12-210

Open Data