Table 1 |
|
| Follicular lymphoma grading according to the WHO classification1 | |
| Grading Definition | |
| Grade 1–2 (low grade) 0–15 centroblasts per hpf* | |
| · 1 0–5 centroblasts per hpf | |
| · 2 6–15 centroblasts per hpf | |
| Grade 3 >15 centroblasts per hpf | |
| · 3A: centrocytes present | |
| · 3B: solid sheets of centroblasts | |
| Follicular Pattern | |
| · Follicular >75% | |
| · Follicular and diffuse 25–75% | |
| · Focally follicular <25% | |
| · Diffuse 0%** | |
* hpf = high-power field of 0.159 mm2.
** Diffuse areas containing >15 centroblasts per hpf are reported as DLBCL with FL (grades 1 to 2, 3A or 3B). Note that in small biopsies the absence of follicles may reflect a sampling error.
Rueda et al. BMC Cancer 2012 12:210 doi:10.1186/1471-2407-12-210
