Open Access Research article

The association between the preoperative serum levels of lipocalin-2 and matrix metalloproteinase-9 (MMP-9) and prognosis of breast cancer

Hyuna Sung1, Ji-Yeob Choi16, Sang-Ah Lee2, Kyoung-Mu Lee3, Sohee Han4, Sujee Jeon5, Minkyo Song4, Yunhee Lee1, Sue K Park146, Keun-Young Yoo4, Dong-Young Noh67, Sei-Hyun Ahn8 and Daehee Kang146*

Author Affiliations

1 Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea

2 Department of Preventive Medicine, Kangwon National University School of Medicine, Kangwon, Korea

3 Department of Environmental Health, Korea National Open University, Seoul, Korea

4 Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea

5 Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine or College of Pharmacy, Seoul National University, Seoul, Korea

6 Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

7 Department of Surgery, Seoul National University College of Medicine, Seoul, Korea

8 Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea

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BMC Cancer 2012, 12:193  doi:10.1186/1471-2407-12-193

Published: 28 May 2012

Additional files

Additional file 1:

Table S1. Serum levels of lipocalin-2 and MMP-9 were compared between breast cancer cases ( N = 303) and age and sex matched healthy controls ( N = 74). Table S2. The predictive accuracy of model using combined score of Lipocalin-2 and MMP-9 and other prognostic factors.

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