Table 4

Multivariate Cox regression analyses of systemic recurrence-free survival, and breast-cancer specific survival according to DTC detection in BM samples drawn at different time points from non-metastatic breast cancer patients
BM samples DTC-positive patients Systemic recurrence-free survival Breast-cancer specific survival
Hazard ratio P-values Hazard ratio P-values
BM1 16% 6.420 <0.001 7.081 <0.001
BM2 12% 5.793 <0.001 6.455 0.001
BM3 6% 6.841 0.004 4.888 0.022
BM2 and/or BM3 15% 5.397 <0.001 5.303 <0.001
BM1 and BM2/3 5% 7.188 <0.001 8.018 <0.001

BM1 drawn prior to surgery; BM2 drawn three weeks after surgery; BM3 drawn six months after surgery.

The different BM samples were included in the models in separate regression experiments. Only results from backward stepwise selection of variables are presented.

Tjensvoll et al.

Tjensvoll et al. BMC Cancer 2012 12:190   doi:10.1186/1471-2407-12-190

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