|Results of quantitative studies examining effects of nihilistic views of health professionals on medical and treatment outcomes|
|Study||Health professionals||Outcome||Main findings|
|Pessimism regarding the use of platinum based chemotherapy for stage IV NSCLC|
|Jennens 2004 Australia||Physicians, medical and radiation oncologists and thoracic surgeons who saw patients with metastatic lung cancer||Referrals for chemotherapy for stage IV NSCLC||Does not examine the effect of pessimism on referrals - the outcome of interest, referrals for chemotherapy, is included as part of the measure of pessimism|
|Pessimists vs realists vs optimists (underestimation vs realistic estimation vs overestimation of survival rate for resected stage I NSCLC)|
|Schroen 2000 USA||Pulmonologists and thoracic surgeons treating adult lung cancer patients||Differences between pessimists, realists and optimists|
|Believe in survival benefit in NSCLC for chemotherapy:|
|As adjuvant for resected stage I-IIIA disease||p = 0.07*|
|In addition to radiotherapy for unresectable locally advanced disease||p < 0.001* lower for pessimists|
|For stage IV disease||p = 0.31*|
|Believe in palliative benefit for chemotherapy for stage IV NSCLC||p = 0.19*|
|Believe in survival benefit for adjuvant radiotherapy in resected stage I-IIIA NSCLC||p = 0.66*|
NSCLC = Non small cell lung cancer; *Chi-squared test.
Chambers et al.
Chambers et al. BMC Cancer 2012 12:184 doi:10.1186/1471-2407-12-184