Systemic therapy according consensus giudelines (St. Gallen). EIC – extensive intraductal component, WBRT – whole breast radiotherapy, SNB – sentinel node-biopsy, BCS – breast conserving surgery L1 – lymphangio invasion *modifications according to local protocols and national guidelines; **with reference to national guidelines a re-resection should be performed in presence of positive resection margins (e.g. <1cm in Germany).
Neumaier et al. BMC Cancer 2012 12:171 doi:10.1186/1471-2407-12-171