Table 2

Disease characteristics by age group

Age < 70 years (N = 333) n (%)

Age ≥ 70 years (N = 188) n (%)

All patients (N = 521) n (%)


Histology


Non-squamous cell carcinoma

283 (85.0)

161 (85.6)

444 (85.2)


Squamous cell carcinomaa

50 (15.0)

27 (14.4)

77 (14.8)


Disease stage at study entry


Stage IIIa

18 ( 5.4)

17 ( 9.0)

35 ( 6.7)


Stage IIIb

65 (19.5)

38 (20.2)

103 (19.8)


Stage IV

250 (74.1)

133 (70.7)

383 (73.5)


Karnofsky Index (KI)


KI ≥ 80%

207 (62.2)

116 (61.7)

323 (62.0)


KI 70%

89 (26.7)

45 (23.9)

134 (25.7)


KI 60%

27 ( 8.1)

18 ( 9.6)

45 ( 8.6)


KI 50%

10 ( 3.0)

8 ( 4.3)

18 ( 3.5)


Missing data

0 ( 0.0)

1 ( 0.5)

1 ( 0.2)


N = total number of patients, n = number of patients

a) The study started in 2007, before the label change in April 2008 which restricted the use of pemetrexed to patients with non-squamous cell carcinoma

Schuette et al. BMC Cancer 2012 12:14   doi:10.1186/1471-2407-12-14

Open Data