Table 1

Clinical and histomorphological data

Parameter

Total (n = 124)

OPN-a mRNA expression

OPN-b mRNA expression

OPN-c mRNA expression


low (n = 62)

high (n = 62)

low (n = 62)

high (n = 62)

low (n = 62)

high (n = 62)


Sex

P = 0.02

P = 0.10

P = 0.37

Male

56

35

21

33

23

31

25

Female

68

27

41

29

39

31

37


Histological subtype

P = 0.96

P = 0.17

P = 0.17

Liposarcoma

27

14

13

14

13

13

14

MFH/Fibrosarcoma

38

17

21

14

24

14

24

NS

15

8

7

9

6

9

6

RMS + LMS

29

15

14

14

15

15

14

other STS

15

8

7

11

4

11

4


Tumor grade

P = 0.03

P = 0.05

P = 0.03

I

16

6

10

6

10

4

12

II

70

42

28

42

28

42

28

III

37

13

24

14

23

16

21


Tumor stage

P = 0.37

P = 0.43

P = 0.33

I

15

7

8

7

8

5

10

II

57

33

24

33

24

33

24

III

40

18

22

17

23

19

21

IV

12

4

8

5

7

5

7


Tumor localization

P = 0.29

P = 0.26

P = 0.30

Extremities

79

37

42

37

42

36

43

Thorax

12

5

7

5

7

6

6

Head and neck

4

1

3

1

3

1

3

Abdominal

27

18

9

17

10

18

9

Other

2

1

1

2

0

1

1


Recurrence

P = 1.00

P = 1.00

P = 1.00

Yes

55

28

27

28

27

27

28

No

69

34

35

34

35

35

34


Lymph node status

P = 0.21

P = 0.21

P = 0.03

N0

118

61

57

61

57

62

56

N1

6

1

5

1

5

0

6


Distant metastases

P = 0.28

P = 0.88

P = 0.88

M0

45

25

20

23

22

23

2

M1

50

20

30

24

26

24

26

Evaluation not possible

3

2

1

2

1

2

1


Radiation

P = 1.00

P = 0.86

P = 0.86

Yes

58

29

29

30

28

30

28

No

66

33

33

32

34

32

34


Chemotherapy

P = 0.74

P = 0.74

P = 0.74

Yes

10

4

6

4

6

4

6

No

114

58

56

58

56

58

56


Abbreviations: MFH - malignant fibrous histiocytoma, NS - neurogenic sarcoma, RMS - rhabdomyosarcoma, LMS - leiomyosarcoma

Hahnel et al. BMC Cancer 2012 12:131   doi:10.1186/1471-2407-12-131

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