JS-K, a glutathione/glutathione S-transferase-activated nitric oxide releasing prodrug inhibits androgen receptor and WNT-signaling in prostate cancer cells
1 Institute for General Zoology and Endocrinology, Ulm University, Albert Einstein Allee 23, 89069 Ulm, Germany
2 Department of Urology, Ulm University, Prittwitzstrasse 43, 89075, Ulm, Germany
BMC Cancer 2012, 12:130 doi:10.1186/1471-2407-12-130Published: 30 March 2012
Additional file 1:
Figure 1S: JS-K does not inhibit AR-dimerization. Complementary data to experiment presented in Figure 3: AR-dimerization was determined in DU-145 cells using the CheckMate Mammalian Two-Hybrid System described in Material and Methods. Results are mean values of three independent experiments performed in quadruplicates. (DOC 20 kb).
Format: TIFF Size: 1.5MB Download file