Table 1

KRAS genotype frequencies in the study population

Study population

Genotype

Frequency

N %

OR (95% CI)

p value


Controls

wild (TT)

221/269 (82.2)

1.0

variable (TG/GG)

48/269 (17.8)


Sporadic cases

wild (TT)

434/524 (82.8)

0.96 (0.65-1.40)

0.814

variable (TG/GG)

90/524 (17.2)


Familial cases

wild (TT)

135/165 (81.8)

1.02 (0.62-1.69)

0.929

variable (TG/GG)

30/165 (18.2)


BRCA carriers

wild (TT)

26/29 (89.7)

0.53 (0.15-1.83)

0.316

variable (TG/GG)

3/29 (10.3)


BRCA1 carriers

wild (TT)

18/20 (90.0)

0.51 (0.12-2.28)

0.379

variable (TG/GG)

2/20 (10.0)


BRCA2 carriers

wild (TT)

8/9 (88.9)

0.58 (0.07-4.71)

0.606

variable (TG/GG)

1/9 (11.1)


Non-BRCA carriers

wild (TT)

109/136 (80.1)

1.14 (0.68-1.93)

0.623

variable (TG/GG)

27/136 (19.9)


Cerne et al. BMC Cancer 2012 12:105   doi:10.1186/1471-2407-12-105

Open Data