Table 1

The common enhancer genes that potentiated the effect of topotecan from three screens

Genes that enhance the effect of topotecan-induced cell death


BIRC4 *, **

BOK *

BBC3

CNTF

ICEBERG

PDCD2

TNFAIP1

CTSD *, **

CDKN2A *

BCL11B

DAP

IGF1

PIK3C2G

TNFAIP2

NFKB1 *, **

CDKN2D *

BCL2A1

DNASE1

IL10RB

PRDX5

TNFSF12

NOS2A *, **

F2R *

BIRC3

DOCK1

IL1B

PRF1

TNFSF5

RIPK1 *, **

MCL1 *

BNIP3

DUSP7

LTB

PTGS1

TP53

TGFB1 *, **

MMP9 *

CARD10

ERCC6

MAP2K6

RAD23B

TRAF1

TNFRSF10A *, **

STK3 *

CARD14

FAF1

MAP3K14

RB1

TRAF6

TNFRSF25 *, **

TNFRSF10D *

CASP9

GPX1

MYB

SFRP5

WDR3

TNFRSF8 *, **

TP53BP2 *

CLU

HSPE1

NOS3

TIA1

YWHAZ


Footnote: *genes present in the second screen (18); ** genes in all three screens (9)

Tsang et al. BMC Cancer 2012 12:101   doi:10.1186/1471-2407-12-101

Open Data