Global and Local Feature Extraction. Global features are extracted from the entire tissue sample, and local features are extracted by sliding a window of a fixed size across the tissue sample and computing summary statistics, such as standard deviation, of window-specific scores. In this example, the global feature "number of nuclei" has value 755, while one example position of the sliding window is shown, with "number of nuclei" = 29.
Kwak et al. BMC Cancer 2011 11:62 doi:10.1186/1471-2407-11-62