Open Access Highly Accessed Research article

Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

Stefan Enroth15, Alvaro Rada-Iglesisas126, Robin Andersson17, Ola Wallerman2, Alkwin Wanders2, Lars Påhlman3, Jan Komorowski14 and Claes Wadelius2*

Author Affiliations

1 The Linnaeus Centre for Bioinformatics, Department of Cell and Molecular Biology, Science for Life Laboratory, Biomedical Center, Uppsala University, Box 598, SE-75124 Uppsala, Sweden

2 Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, SE-75185 Uppsala, Sweden

3 Department of Surgical Sciences, Uppsala University, SE-75185 Uppsala, Sweden

4 Interdisciplinary Centre for Mathematical and Computational Modelling, Warsaw University, PL-02-106 Warszawa, Poland

5 Current address: Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, SE-75185 Uppsala, Sweden

6 Current address: Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California 94305, USA

7 Current address: Department of Biology, Bioinformatics Centre, University of Copenhagen, Ole Maaloes Vej 5 DK-2200, Copenhagen N, Denmark

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BMC Cancer 2011, 11:450  doi:10.1186/1471-2407-11-450

Published: 19 October 2011

Additional files

Additional file 1:

Marked genes: Lists of genes enriched with H3K4me3 or H3K27me3 in patient material or cell line.

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Additional file 2:

Supplementary Material: 6 figures and 2 tables.

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