Table 1

Baseline characteristics for all cases with primary cancer and their matched controls with at least 6 years of medical records

Cases (N = 88125)

Controls (N = 362254)


Sex


female

41749 (47.4)

170173 (47.0)


male

46376 (52.6)

192081 (53.0)


Age band (years)


30-54

13151 (14.9)

49906 (13.8)


55-64

19638 (22.3)

80107 (22.1)


65-74

26758 (30.4)

111698 (30.8)


75-84

25013 (28.4)

106278 (29.3)


85 +

3565 (4.0)

14265 (3.9)


Deprivation


Townsend quintile 1, most affluent

22072 (25.0)

92287 (25.5)


Townsend quintile 2

18998 (21.6)

79067 (21.8)


Townsend quintile 3

17338 (19.7)

71358 (19.7)


Townsend quintile 4

15325 (17.4)

61767 (17.1)


Townsend quintile 5, most deprived

11896 (13.5)

45971 (12.7)


Townsend missing

2496 (2.8)

11804 (3.3)


Body mass index (kg/m2)


15-24

26721 (30.3)

105883 (29.2)


25-29

27285 (31.0)

108803 (30.0)


30-49

12922 (14.7)

51413 (14.2)


not recorded

21197 (24.1)

96155 (26.5)


Smoking status


non-smoker

54307 (61.6)

233135 (64.4)


ex-smoker

7567 (8.6)

23842 (6.6)


current smoker

17275 (19.6)

54869 (15.1)


not recorded

8976 (10.2)

50408 (13.9)


Co-morbidities


Cardiovascular disease

14278 (16.2)

58123 (16.0)


Diabetes

7115 (8.1)

26802 (7.4)


Hypertension

27104 (30.8)

109797 (30.3)


Osteoarthritis

12807 (14.5)

52586 (14.5)


Rheumatoid arthritis

1310 (1.5)

5132 (1.4)


Colitis1

124 (1.1)

293 (0.6)


Crohn's disease1

28 (0.2)

109 (0.2)


Benign breast disease2

1094 (7.0)

2937 (4.7)


Family history of breast cancer2

539 (3.4)

1249 (2.0)


Medications (in previous 13-72 months)


NSAID

35697 (40.5)

140642 (38.8)


COX2 inhibitors

6901 (7.8)

26974 (7.4)


Aspirin

19895 (22.6)

79067 (21.8)


Hormone replace therapy2

3289 (21.0)

10973 (17.4)


Oral contraceptive pill2

523 (3.3)

1638 (2.6)


1) Based only on cases with colorectal cancer and their controls

2) Based only on female cases with breast cancer and their controls

Vinogradova et al. BMC Cancer 2011 11:409   doi:10.1186/1471-2407-11-409

Open Data