Table 5

ORs of breast cancer associated with total intake of antioxidants, NECSS,Canada,1994-1997

Premenopausal

Postmenopausal



Variable

Cases

Controls

OR † (95% CI)

p

Cases

Controls

OR†† (95% CI)

p


Beta-carotene

From Diet only

Low or no intake

423

435

1.00

781

837

1.00

High intake *

443

410

1.09 (0.88-1.34)

0.43

715

780

0.96 (0.82-1.13)

0.66

From supplementation only

Low or no intake

864

836

1.00

1487

1598

1.00

High intake**

2

9

0.11 (0.01-0.88)

0.04

9

19

0.47 (0.20-1.08)

0.07

From both sources

Low or no intake

856

833

1.00

1473

1589

1.00

High intake***

10

12

0.77 (0.32-1.87)

0.57

23

28

0.69 (0.37-1.27)

0.23

Vitamin C (years)

From Diet only

Low or no intake

467

489

1.00

861

962

1.00

High intake *

399

356

1.23 (0.99-1.53)

0.06

635

655

1.24 (0.99-1.42)

0.07

From supplementation only

Low or no intake

823

794

1.00

1405

1524

1.00

High intake**

43

51

0.70 (0.44-1.10)

0.12

91

93

0.85 (0.61-1.17)

0.32

From both sources

Low or no intake

812

779

1.00

1352

1463

1.00

High intake***

54

66

0.65 (0.44-0.98)

0.04

144

154

0.78 (0.60-1.03)

0.08

Vitamin E (years)

From Diet only

Low or no intake

451

454

1.00

837

922

1.00

High intake *

415

391

0.98 (0.78-1.22)

0.85

659

695

1.06 (0.89-1.25)

0.53

From supplementation only

Low or no intake

852

828

1.00

1451

1555

1.00

High intake**

14

17

0.72 (0.33-1.59)

0.42

45

62

0.64 (0.42-0.99)

0.04

From both sources

Low or no intake

841

814

1.00

1392

1503

1.00

High intake***

25

31

0.71 (0.40-1.25)

0.23

104

114

0.86 (0.64-1.17)

0.35

Zinc (years)

From Diet only

Low or no intake

430

451

1.00

747

855

1.00

High intake *

436

394

1.13 (0.89-1.45)

0.32

749

762

1.13 (0.94-1.35)

0.20

From supplementation only

Low or no intake

859

830

1.00

1487

1597

1.00

High intake**

7

15

0.29 (0.10-0.83)

0.02

9

20

0.41 (0.18-0.96)

0.04

From both sources

Low or no intake

855

831

1.00

1478

1590

1.00

High intake***

11

14

0.73 (0.31-1.72)

0.47

18

27

0.51 (0.27-0.97)

0.04

Selenium (years)

From Diet only

Low or no intake

417

426

1.00

747

822

1.00

High intake *

449

419

1.01 (0.79-1.29)

0.93

749

795

0.99 (0.82-1.18)

0.88

From supplementation only

Low or no intake

861

834

1.00

1488

1604

1.00

High intake**

5

11

0.39 (0.13-1.16)

0.09

8

13

0.50 (0.19-1.32)

0.16

From both sources

Low or no intake

861

842

1.00

1480

1603

1.00

High intake***

5

3

1.77 (0.33-9.69)

0.51

16

14

0.82 (0.37-1.80)

0.61


† Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, number of live births, age at menarche, and total energy intake.

†† Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, BMI, recreational physical activity, number of live births, age at menarche, and total energy intake.

* In comparison with low intake (lower than median intake).

** In comparison with low intake (less than 10 years of supplementation).

*** In comparison with not high intake from both sources.

Pan et al. BMC Cancer 2011 11:372   doi:10.1186/1471-2407-11-372

Open Data