Table 3

Distribution of QoL scores by stage of disease and prior treatment history

QLQ-C30 Scale

Stage of disease

Treatment History

Locoregional

(N = 511)

Metastatic

(N = 656)

P

Newly diagnosed

(N = 605)

Previously treated

(N = 589)

P


Global

53.8

53.1

0.63

56.1

50.8

0.001

Physical

69.4

68.0

0.35

73.1

64.1

< 0.001

Role

60.4

57.2

0.12

62.4

55.2

< 0.001

Emotional

64.5

63.5

0.55

63.3

64.8

0.33

Cognitive

75.1

74.5

0.68

75.9

73.7

0.16

Social

62.0

60.2

0.35

65.3

56.8

< 0.001

Fatigue

45.0

48.6

0.03

43.1

50.6

< 0.001

Nausea/Vomiting

13.9

15.1

0.36

12.2

16.8

< 0.001

Pain

34.7

39.0

0.02

34.0

40.3

0.001

Dyspnea

39.5

36.0

0.08

34.7

40.6

0.002

Insomnia

39.0

41.0

0.31

40.5

39.3

0.54

Appetite Loss

30.2

32.3

0.29

28.4

34.1

0.004

Constipation

22.7

25.4

0.14

23.2

25.2

0.27

Diarrhea

9.9

9.8

0.92

8.8

10.9

0.07


Higher scores in the global and functioning scales and lower scores in the symptom scales indicate better QoL.

Braun et al. BMC Cancer 2011 11:353   doi:10.1186/1471-2407-11-353

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