Additional file 1.

Association of tumour size (A), histological grade (B) and lymph node status (C) to high scores of NPI in TNBC. The boxplot graphic show an association between larger tumours, displaying high histological grade and with extensive lymph node invasion, with tumours clustered into the worst outcome group, represented by NPI > 5.4 (p < 0.0001) (A, B and C). The graphic highlights the contribution of lymph node status to the augmentation of NPI, showing that LNS is a determinant factor to predict worse prognosis in TNBC patients.

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Albergaria et al. BMC Cancer 2011 11:299   doi:10.1186/1471-2407-11-299