Table 2

Risk factors for lung cancer for HIV patients and population controls

Lung cancer (HIV/population controls), N

Unadjusted IRR (95% CI)

Adjusted IRR* (95% CI)


All

29/183

2.08 (1.41 - 3.08)

2.38 (1.61 - 3.53)


Stratification


Male gender*

27/156

2.33 (1.55 - 3.50)

2.66 (1.77 - 4.01)

Female gender

2/27

0.91 (0.22 - 3.82)

**

Native

24/179

2.13 (2.39 - 3.27)

2.56 (1.47 - 3.46)

Immigrant

5/4

6.38 (1.71 - 23.86)

**

Younger than or 50 years at index date

18/104

2.33 (1.35 - 4.04)

2.34 (1.35 - 4.06)

Older than 50 years at index date *

14/98

2.07 (1.18 - 3.63)

2.08 (1.19 - 3.65)

HIV diagnosed before 1995

18/112

2.34 (1.42 - 3.85)

2.60 (1.58 - 4.28)

HIV diagnosed after 1995 at index date

11/71

1.75 (0.93 - 3.31)

2.13 (1.12 - 4.03)

Smoker or former smoker in any quantity

29/81

3.79 (2.48 - 5.97)

4.06 (2.66 - 6.21)

Never smoked

0/35

**

**

Route of HIV infection

Men who have sex with men (MSM)

12/99

1.60 (0.88 - 2.91)

1.82 (0.99 - 3.12)

Heterosexually infected men

12/44

3.40 (1.80 - 6.45)

4.19 (2.20 - 7.96)

Heterosexually infected women

2/18

1.26 (0.30 - 5.44)

**

Injection drug user (IDU)

3/13

1.95 (1.28 - 2.94)

**

Baseline CD4 < 350 cells/μL or AIDS defining event at index date

20/111

2.70 (1.68 - 4.35)

3.25 (2.01 - 5.24)

Baseline CD4 350 cells/μL and no AIDS defining event at index date

6/40

1.68 (0.71 - 3.96)

1.71 (0.72 - 4.03)


* All adjusted for gender and age, except the stratification on male which is only adjusted for age and age > 50 which is only adjusted for gender.

** Too few events for analysis.

Engsig et al. BMC Cancer 2011 11:272   doi:10.1186/1471-2407-11-272

Open Data