Effect of 10%FS diet on lung lipid peroxidation levels 4 months post-XRT. Mice were fed with 0% or 10%FS diet prior (-3 weeks) or post (+2, +4, +6 weeks) X-ray radiation therapy (XRT). Lungs were harvested after 4 months, homogenized and assayed for lipid peroxidation by measuring Malondialdehyde (MDA) levels. MDA is calculated per g of wet lung tissue. Data is represented mean ± SEM of two independent experiments (n = 15-25 mice per group). The white, black, gray and hatched bars represent untreated control, 0%FS + XRT, 10%FS and 10%FS + XRT groups, respectively. *p ≤ 0.0002 for irradiated 0%FS vs. irradiated 10%FS.
Christofidou-Solomidou et al. BMC Cancer 2011 11:269 doi:10.1186/1471-2407-11-269