Table 2

AQP1, -3, -4, -5 and -9 gene expression in 105 NSCLC and normal samples by qRT-PCR data

AQP isoform

Tumor vs Normal

AC vs SCC

AC MT vs MN

SCC MT vs MN

Survival in AC: Good vs Bad


p-value

Fold change

p-value

Fold change

p-value

Fold change

p-value

Fold change

p-value

Fold change


AQP1

0.0000

0.22

0.0228

2.36

0.0000

0.26

0.0000

0.10

0.0340

2.86


AQP3

0.7089

0.93

0.0005

5.81

0.0205

1.76

0.0676

0.38

0.7165

0.81


AQP4

0.0000

0.11

0.0144

5.96

0.0000

0.12

0.0002

0.02

0.0344

4.42


AQP5

0.0253

0.50

0.3255

1.88

0.1640

0.55

0.1956

0.39

0.1937

0.25


AQP9

0.7384

1.05

0.1310

0.64

0.6103

0.91

0.7887

1.12

0.7480

1.15


Student's T-Test comparison between matched tumor (MT) and normal lung tissue (MN) collectives (n = 45), different histology (AC vs SCC) and survival (good >3 y, bad <3 y).

AQP: aquaporin; AC: adenocarcinoma; SCC: squamous cell carcinoma; p-value and fold change in bold indicate statistical significance.

Warth et al. BMC Cancer 2011 11:161   doi:10.1186/1471-2407-11-161

Open Data