AQP4-protein expression pattern in NSCLCs. AQP4 is mainly expressed in well differentiated AC (A), and to a lower extent in moderately differentiated AC (B). SCC are mostly negative for AQP4, but have AQP4-positive intra-tumoral alveolar cells (C). D shows AQP4 expression in a pleomorphic carcinoma. Magnification ×20.
Warth et al. BMC Cancer 2011 11:161 doi:10.1186/1471-2407-11-161