Table 2 |
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|
ZIC-like immunoreactivities in brain tumors |
|||
|
CXY2 |
ZC26 |
ZIC4 nuc_stain* |
|
|
|
|||
|
Grade I Meningioma |
++ (12/22) |
++ (2/22) |
- (22/22) |
|
+ (7/22) |
+ (14/22) |
||
|
± (3/22) |
± (6/22) |
||
|
|
|||
|
Grade II Meningioma** |
++ (1/1) |
++ (1/1) |
- (1/1) |
|
|
|||
|
Grade III Meningioma** |
++ (1/1) |
+ (1/1) |
- (1/1) |
|
|
|||
|
Medulloblastoma |
++ (4/4) |
++ (4/4) |
++ (4/4) |
|
|
|||
|
Glioblastoma |
± (1/4) |
||
|
- (4/4) |
- (3/4) |
- (4/4) |
|
|
|
|||
|
Hemangioblastoma |
± (2/4) |
± (1/4) |
|
|
- (2/4) |
- (3/4) |
- (4/4) |
|
|
|
|||
|
Primitive neuroectodermal tumor |
+ (1/1) |
+ (1/1) |
- (1/1) |
|
|
|||
|
Atypical teratoid rhabdoid tumor |
+ (1/1) |
+ (1/1) |
- (1/1) |
|
|
|||
|
Intensity of the staining: -, none; ±, low; +, medium; ++, high. *, Although ZIC4 antibodies gave both nuclear and cytoplasmic staining, only the nuclear staining (nuc_stain) were evaluated. **, these two specimens derive from the same patient at different stages. |
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|
Aruga et al. BMC Cancer 2010 10:79 doi:10.1186/1471-2407-10-79 |
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