Estrogen has no effect on HAX1 expression. Preconditioned cells were treated with the increasing concentrations of beta-estradiol for 48 h. mRNA levels of HAX1 and estrogen-dependent cathepsin D mRNA were measured by quantitative PCR. A. Estrogen-dependent breast cancer cell line MCF-7. B. HeLa cell line.
Trebinska et al. BMC Cancer 2010 10:76 doi:10.1186/1471-2407-10-76