HAX1 (splice variant I) expression levels in eight different solid tumors. HAX1 expression is significantly elevated in breast (A), lung (B) and colon (C) cancers, while in kidney (D), liver (E), ovary (F), prostate (G) and thyroid (H) cancers up-regulation was not detected. Quantitative data from cDNA panels were analyzed using the nonparametric Mann-Whitney test. Statistical significance was denoted under the box-whiskers plots for values of P < 0.05. In breast and lung cancers significant overexpression was observed for the advanced stages (III-IV), while in colon cancer for early stages (I-II).
Trebinska et al. BMC Cancer 2010 10:76 doi:10.1186/1471-2407-10-76