Table 5

Comparison of qPCR data and NotI-microarrays for RBSP3 gene

Sample number

qPCR

bNot I-microarrays

Possible reason of mRNA decrease

mRNA

decrease

aDNA

copy number


AC

1

0.39

+

+

deletion

2

0.15

-

+

methylation

4

0.29

-

-

another mechanism

5

0.49

+

+

deletion

7

0.37

-

-

another mechanism

11

0.12

-

-

another mechanism

16

0.29

-

+

methylation

17

0.12

-

+

methylation

SCC

23

0.16

-

+

methylation

25

0.13

+

+

deletion and methylation

26

0.21

-

+

methylation

27

0.39

+

+

deletion and methylation

43

0.48

-

+

deletion

46

0.14

-

+

methylation

52

0.06

-

+

methylation

53

0.46

-

+

methylation

54

0.08

-

+

methylation

55

0.26

-

-

another mechanism


a + deletion, - retention

b+ deletion and/or methylation, - no changes

Senchenko et al. BMC Cancer 2010 10:75   doi:10.1186/1471-2407-10-75

Open Data