Table 4

The frequencies of simultaneous mRNA level decreases (FD) for the combination of genes RBSP3, NPRL2/G21 and RASSF1A in different groups

Groups

aFD, (%)

RBSP3

/NPRL2/G21

RBSP3/

RASSF1A

RASSF1A/

NPRL2/G21

RBSP3/NPRL2/G21

/RASSF1A


AC

I

14 (1/7)

14 (1/7)

0 (0/7)

0 (0/7)

II+III

71 (5/7)

rs= 0.88

100 (7/7)

rs= 0.88

71 (5/7)

rs= 0.74

71 (5/7)

Total

43 (6/14)

57 (8/14)

36 (5/14)

36 (5/14)

SCC

I

67 (4/6)

17 (1/6)

33 (2/6)

17 (1/6)

II+III

75 (12/16)

rs= 1.00

56 (9/16)

rs= 0.88

56 (9/16)

rs= 0.88

50 (8/16)

Total

73 (16/22)

rs= 0.94

45 (10/22)

rs = 0.74

50 (11/22)

rs = 0.69

41 (9/22)

NSCLC

I

38 (5/13)

15 (2/3)

15 (2/3)

8 (1/13)

II+III

74 (17/23)

70 (16/23)

61 (14/23)

57 (13/23)

Total

61 (22/36)

rs = 0.72

50 (18/36)

rs = 0.68

44 (16/36)

rs = 0.63

39 (14/36)


aNumber of cases with reduced mRNA level/to all cases is shown in parenthesis

bGroup I without metastases, group II+III -- with metastases

cThe rs are the Spearmen's coefficient values of rank correlation. Bold designates the highest correlations between pairs of genes. P < 0.001 in all groups

Senchenko et al. BMC Cancer 2010 10:75   doi:10.1186/1471-2407-10-75

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