Table 3

Clinicopathologic parameters and AGR2 expression in patients with high stage prostate cancer

Stage III/IV patients

Mean AGR2

expression (SE)

P-value

Low AGR2

High AGR2

P-value


Total cases

65

0.53 (0.057)

44

21

Age at surgery

0.7622

0.7631

Median (range)

66 (50-76)

66 (50-76)

65 (50-73)

Mean

64.6

64.8

64.3

Gleason score

0.0981

0.1613

2-6

22

0.664 (0.104)

12

10

7-10

43

0.457 (0.066)

32

11

pT stage

0.4511

0.1113

pT2-pT3a

30

0.565 (0.087)

17

13

pT3b

35

0.495 (0.076)

27

8

Lymph node status

0.1181

0.4803

Positive

11

0.353 (0.118)

9

2

Negative

54

0.563 (0.064)

35

19

Tumor margins

0.9901

0.7943

Positive

35

0.536 (0.087)

23

12

Negative

30

0.517 (0.072)

21

9

Capsular invasion

0.8051

> 0.9993

No invasion

4

0.507 (0.174)

3

1

Invasion

61

0.529 (0.060)

41

20

PSA ng/mL

0.4142

0.0891

Median (range)

11.9 (2.1-96.5)

0.3531

0.0923

Mean

18.7

< 10

25

0.607 (0.103)

14

11

≥10

32

0.463 (0.073)

25

7


1Mann-Whitney, 2Spearman Correlation, 3Fisher's Exact Test. Cases that were uninformative for a given variable were removed from the statistical analysis.

Maresh et al. BMC Cancer 2010 10:680   doi:10.1186/1471-2407-10-680

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