Table 2

The 2-year OS and DFS rates associated with ovarian fibrosarcoma patients and Cox proportional hazard regression analysis of patient survival based on clinical and pathologic factors

Variables

Case (%)

2 year's rate

2 year's rate

Cox (OS)

Cox (DFS)


Univariate

Multivariate

Univariate

Multivariate


OS

X2

P

DFS

X2

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P


Age (years)

< 45

15 (48.4)

66

60

≥ 45

16 (51.6)

45.4

0.879

0.348

27.8

1.476

0.224

1.731 (0.540-5.545)

0.356

1.882 (0.658-5.382)

0.238

FIGO stage

I a - I c

14 (45.2)

77.1

68.4

II a - III c

17 (54.8)

36.2

6.041

0.014

22.9

8.964

0.003

4.525 (1.210-16.916)

0.025

10.156 (2.021-51.023)

0.005

4.914 (1.538-15.704)

0.007

18.761 (1.674-210.288)

0.017

Largest diameter (cm)

< 10

11 (45.8)

43.2

44.4

≥ 10

13 (54.2)

54.7

0.069

0.793

38.9

0.187

0.666

0.844 (0.236-3.014)

0.794

1.302 (0.389-4.360)

0.669

Mitoses/10 HPFs

< 4

22 (71.0)

49.7

48

≥ 4

9 (29.0)

70

0.632

0.426

41.7

0.046

0.83

0.545 (0.119-2.499)

0.435

1.132 (0.358-3.575)

0.833

Ki-67 (MIB-1)-positive

< 10

5 (26.3)

100

66.7

≥ 10

14 (73.7)

27.2

4.148

0.042

36.3

3.138

0.076

51.792 (0.053-5058)

0.261

5.862 (0.668-51.416)

0.11

Therapy

BAO/OR/CT/BAO+RT/OR+RT

20 (64.5)

27.9

28.5

BAO+CT

11 (35.5)

100

9.462

0.002

72.9

6.97

0.008

0.070 (0.008-0.574)

0.013

0.029 (0.003-0.319)

0.004

0.197 (0.052-0.741)

0.016

0.071 (0.005-0.992)

0.049


HR, hazard ratio; CI, confidence interval; OS, overall survival; DFS, disease-free survival; CS, cytoreductive surgery; OR, oophorectomy; CT, chemotherapy; RT, radiotherapy; BA0, a total hysterectomy with bilateral adnexectomy and an omentectomy

Huang et al. BMC Cancer 2010 10:585   doi:10.1186/1471-2407-10-585

Open Data