Open Access Highly Accessed Research article

Methylation status of individual CpG sites within Alu elements in the human genome and Alu hypomethylation in gastric carcinomas

Shengyan Xiang, Zhaojun Liu, Baozhen Zhang, Jing Zhou, Bu-Dong Zhu, Jiafu Ji and Dajun Deng*

Author Affiliations

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing Cancer Hospital and Institute, Peking University School of Oncology, Fu-Cheng-Lu, No.52, Haidian District, Beijing, 100142, China

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BMC Cancer 2010, 10:44  doi:10.1186/1471-2407-10-44

Published: 17 February 2010

Additional files

Additional file 1:

Table S1. - Correlation coefficients of methylation status between each CpG site and Alu clone subgroups with various methylated CpGs. All of 427 Alu clones were classified into different subgroups according to the methylated-CpG number. Average methylation frequency of each CpG site within each Alu subgroup was calculated (methylated-CpG number of the CpG site to the clone number of Alu within the subgroup). The correlation coefficient was calculated for each CpG site based on the corresponding average methylation frequency within each subgroup and the total methylated-CpG number within the subgroup.

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