Treatment with Iripallidal decreases STAT3 phosphorylation in glioma cells. Western blotting analysis demonstrates a decrease in pSTAT3 levels in A172, LN229, T98G and U87MG glioma cells upon Iripallidal treatment. Representative blot is shown from three independent experiments with identical results. C and I denote control and Iripallidal, respectively. Blots were reprobed for β-actin to establish equivalent loading.
Koul et al. BMC Cancer 2010 10:328 doi:10.1186/1471-2407-10-328