Table 5 |
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|
The association between family history of previous cancer and risk of lung cancer in a population based case-control study, Greater Toronto Area, Ontario, 1997-2002 |
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|
Total Population n = 1393 |
Never smokers n = 622 |
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|
|
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|
Case, n |
Control, n |
ORa |
95%CI |
Case, n |
Control, n |
ORb |
95%CI |
|
|
445 |
948 |
156 |
466 |
|||||
|
No family history of any cancer |
246 |
563 |
1.0 |
Refc |
95 |
293 |
1.0 |
Refd |
|
Positive family history of any cancer |
||||||||
|
1 |
141 |
292 |
1.1 |
0.8-1.4 |
42 |
134 |
0.9 |
0.6-1.4 |
|
2 or more |
58 |
93 |
1.3 |
0.9-1.9 |
19 |
39 |
1.4 |
0.8-2.8 |
|
Affected relatives age at onset < 50 |
82 |
126 |
1.3 |
0.9-1.9 |
28 |
48 |
1.8 |
1.0-3.2 |
|
Positive family history of aero-digestive cancer |
45 |
78 |
1.2 |
0.8-1.8 |
11 |
34 |
0.9 |
0.4-1.9 |
|
Positive family history of lung cancer |
30 |
63 |
1.0 |
0.6-1.7 |
8 |
26 |
0.9 |
0.4-2.1 |
|
|
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|
aAdjusted for pack-years smoking, age, sex, education and ethnicity bAdjusted for age, sex, education and ethnicity cReference group consists of all participants with no family history of cancer dReference group consists of never smokers with no family history of cancer |
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|
Brenner et al. BMC Cancer 2010 10:285 doi:10.1186/1471-2407-10-285 |
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