Venn diagram of Significantly Expressed Genes. To be considered present, the transcript had to receive a "Present" call on all three samples. 6946 of the 22215 probes on the array were identified as "present" in all 3 sample pairs (15,269 were absent or marginal) and ~50% of the identified genes (3452) were expressed in both epithelial and stromal tissue. Forty-two percent of the identified genes (2911) were more highly expressed in stromal cells (red) and only 8% (583 genes) were more highly expressed in epithelial cells (blue). The abundance of gene expression in stromal tissue is consistent with its cellular heterogeneity.
Gregg et al. BMC Cancer 2010 10:165 doi:10.1186/1471-2407-10-165