Table 3

An internal dose-response analysis.

ICD-10

Site

Digitoxin concentration ng/ml

<16

16–22

>22

C50

Breast

1.00 (reference)

1.04(0.59, 1.84)

0.90(0.48, 1.67)

C61

Prostate

1.00 (reference)

0.79(0.51, 1.22)

0.89(0.56, 1.40)

C18–C21

Colo-rectal

1.00 (reference)

0.97(0.66, 1.42)

0.92(0.61, 1.40)

C32–C34

Lung

1.00 (reference)

1.25(0.71,2.22)

1.06(0.57,2.00)

C64, C65

Kidney, urinary

1.00 (reference)

0.30(0.15,0.57)

0.45 (0.24, 0.83)

C67, C68

organs

C43,C44

Melanoma, other

1.00 (reference)

1.16(0.60,2.25)

1.29(0.65,2.57)

skin

C81–C85

Leukemia and

1.00 (reference)

0.67(0.38, 1.18)

0.57(0.30, 1.08)

C88–C92

Lymphoma

C00-C97

All sites

1.00 (reference)

0.84(0.71,0.99)

0.86(0.72, 1.02)

An internal dose-response analysis. Age-adjusted relative risks (95% confidence limits) of specific types of cancer by concentration levels (tertiles) of digitoxin. A Cox regression analysis was used.

Haux et al. BMC Cancer 2001 1:11   doi:10.1186/1471-2407-1-11