Table 14

Interventions with evidence of synergistic impact on stillbirth and maternal and neonatal health outcomes

Evidence of stillbirth reduction

Maternal benefit

Neonatal/infant benefit

Antenatal multiple micronutrient supplementation


Reduced anemia (iron-containing supplements)

Improved micronutrient status and survival

Balanced protein-energy supplementation


Improved nutritional status

Reductions in low birth weight

Maternal deworming


Reduced anemia, improved nutritional status

Syphilis screening and treatment


Eradication of syphilis infection

Reductions in congenital syphilis (neonatal morbidity and mortality)

Malaria chemoprophylaxis


Reduced burden of malaria and anemia, reduced maternal mortality

Insecticide-treated bed net use in pregnancy


Reduced burden of malaria and anemia, reduced maternal mortality

Intrapartum cardiotocography with or without pulse oximetry



Reduced birth asphyxia, neonatal mortality

Emergency obstetric care packages


Reduced maternal morbidity and mortality

Reduced neonatal morbidity and mortality

* Some evidence of benefit

** Clear evidence of benefit

1Based on observational data

Bhutta et al. BMC Pregnancy and Childbirth 2009 9(Suppl 1):S7   doi:10.1186/1471-2393-9-S1-S7

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