Table 2

Multivariate Regression Coefficients for the Association of Maternal Risk Factors with Placental Weight, Thickness and Chorionic Plate Area by Placental Growth

Placental Growth

    Placental Restriction

(< 10th percentile)

    Placental Hypertrophy

(> 90th percentile)


Weight

(g)

Thickness

(mm)

Chorionic

Plate Area

(cm2)

Weight

(g)

Thickness

(mm)

Chorionic

Plate Area

(cm2)


Maternal age (per 5 years)

1.00 (0.99, 1.01)

1.02* (1.01, 1.03)

0.99* (0.98, 0.99)

1.01 (1.00, 1.02)

0.99 (0.98, 1.00)

1.04* (1.03, 1.05)

AnnualFamily Income

< $5,000 vs ≥ $5,000

0.88 (0.80, 0.98)

0.79* (0.71, 0.89)

0.87 (0.79, 0.96)

1.19* (1.08, 1.32)

0.92 (0.83, 1.02)

1.21* (1.07, 1.34)

Maternal Education

< 12 yrs vs ≥ 12 yrs

0.83* (0.76, 0.91)

0.78* (0.71, 0.86)

0.87* (0.80, 0.95)

1.09 (0.99, 1.19)

1.15 (1.04, 1.26)

0.94 (0.85, 1.04)

Maternal Race

Black vs White

1.66* (1.51, 1.82)

3.22* (2.90, 3.58)

1.36* (1.24, 1.49)

0.57* (0.51, 0.63)

0.70* (0.64, 0.77)

0.80* (0.72, 0.89)

Smoking Status

Light vs Non-smoker

0.92 (0.84, 1.02)

1.03 (0.93, 1.13)

0.94 (0.86, 1.03)

0.95 (0.85, 1.05)

0.89 (0.81, 0.99)

1.09 (0.98, 1.21)

Heavy vs Non-smoker

1.00 (0.89, 1.13)

1.11 (0.98, 1.27)

0.92 (0.82, 1.03)

0.96 (0.85, 1.09)

0.85 (0.75, 0.97)

1.12 (0.98, 1.27)

Parity

Parous vs Nulliparous

0.89 (0.80, 0.98)

0.98 (0.88, 1.10)

1.06 (0.96, 1.17)

1.25* (1.11, 1.40)

1.32* (1.18, 1.48)

1.09 (0.96, 1.23)

Anemia

Yes vs No

0.67* (0.60, 0.74)

1.00 (0.91, 1.56)

0.80* (0.72, 0.89)

1.50* (1.34, 1.67)

1.18 (1.05, 1.32)

1.45* (1.30, 1.63)

Gestational Diabetes

Yes vs No

0.77 (0.51, 1.16)

0.77 (0.51, 1.18)

0.68 (0.45, 1.02)

1.75* (1.33, 2.32)

1.29 (0.94, 1.76)

1.59* (1.18, 2.13)

Hypertensive Disease

Yes vs No

1.98* (1.54, 2.55)

1.19 (0.91, 1.56)

1.86* (1.46, 2.37)

0.62* (0.46, 0.84)

0.69 (0.50, 0.95)

0.89 (0.66, 1.19)

Pre-pregnancy BMI (per 1 kg/m2)

0.91* (0.90, 0.92)

0.98* (0.97, 0.99)

0.93* (0.92, 0.95)

1.10* (1.06, 1.08)

1.05* (1.04, 1.06)

1.04* (1.03, 1.05)

Pregnancy Weight Gain (per 1 kg)

0.93* (0.92, 0.94)

0.99 (0.98, 1.00)

0.96* (0.95, 0.97)

1.07* (1.06, 1.08)

1.03* (1.02, 1.04)

1.05* (1.04, 1.06)


*P < 0.0045 (Bonferroni-adjusted p-value applied for significance testing)

All results presented as Regression co-efficient (95% Confidence Interval)

Baptiste-Roberts et al. BMC Pregnancy and Childbirth 2008 8:44   doi:10.1186/1471-2393-8-44

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