Table 3

Laboratory data (geometric mean and 95% confidence interval) for young women participants (age 19–44 years) in Phase I and Phase II

Characteristic

Phase I

Phase II

p value


Total participants (n)

233

204

Serum folate (nmol/L)

13.5 (12.9 – 14.1)

18.1 (17.3 – 18.9)

<0.001

RBC folate (mol/L)

625 (601 – 649)

818 (784 – 854)

<0.001

Plasma HCY (μmol/L)

10.2 (9.8 – 10.7)

9.2 (8.8 – 9.6)

0.001

Serum vitamin B12 (pmol/L)

177 (169 – 186)

200 (190 – 211)

0.02

Plasma MMA (μmol/L)

0.18 (0.17 – 0.19)

0.21 (0.19 – 0.22)

0.008


† P value for the difference between Phase I and Phase II is based on a non-parametric Mann-Whitney U test.

RBC denotes red blood cell, HCY denotes homocysteine, and MMA refers to methylmalonic acid.

Liu et al. BMC Pregnancy and Childbirth 2004 4:20   doi:10.1186/1471-2393-4-20

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