Table 1

Domains and Items of the AGREE Instrument
AGREE Domain AGREE Item
Scope and purpose The overall objective of the guideline is specifically described
The clinical question covered by the guideline is specifically described
The patients to whom the guideline is meant to apply are specifically described
Stakeholder involvement The guideline development group includes individuals from all relevant professional groups
The patients’ view and preferences have been sought
The target users of the guideline are clearly defined
The guideline has been piloted among target users
Rigour of development Systematic methods were used to search for evidence
The criteria for selection of the evidence are clearly described
The methods used for formulating recommendations are clearly described
The health benefits, side effects and risks have been considered in formulating the recommendations
There is an explicit link between recommendations and supporting evidence
The guideline has been externally reviewed by experts prior to its publication
A procedure for updating the guideline is provided
Clarity and presentation The recommendations are specific and unambiguous
The different options for the management of the condition are clearly presented
Key recommendations are easily identifiable
The guideline is supported with tools for application
Applicability The potential organizational barriers in applying the recommendations have been discussed
The potential cost implications of applying the recommendations have been considered
The guideline presents a key review criteria for monitoring and/or audit purposes
Editorial independence The guideline is editorially independent from the funding body
Conflicts of interest of guideline development members have been recorded

Greuter et al.

Greuter et al. BMC Pregnancy and Childbirth 2012 12:58   doi:10.1186/1471-2393-12-58

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