Table 1

Main characteristics of the studies included

Study

N

Incidence of GDM (%)1

Ethnicity

Maternal age 2

Gestational age at OGGT (weeks) 2

Pre-gravid BMI2

Study criteria for GDM treatment 3 mmol/L


Aberg 2001 [12] Sweden

4773

5.2

Not reported

Not reported

25-30

Not reported

2 hs PG > 9.0


Black 2010 [13] USA

8711

19.4

White: 7.2; Black: 10.;1 Hispanic: 74.4; Asian: 7.4; Other: 0.9

29.1 ± 5.9

26.7 ± 2.9

27.5 ± 6.1

At least 2 abnormal values: FPG ≥ 5.5; 1 hPG ≥ 10.8; 2 hPG ≥ 8.9


EBDG 2001 [16] Brazil

4998

7.5

White: 44.9 Mixed: 41.1 Black: 13.6 Other: 0.4

27.8 ± 5.5

24-28

23.4 ± 4.0

2 hPG ≥ 10.0


Forsbach 1997 [14] Mexico

667

16.0

Hispanic

18 - 44

34.2 (24-40)

Not reported

2 hPG > 10.0


HAPO 2008, 2010 [7,19] multi-countries

23316

11.4

White: 48.3 Black: 11.6 Hispanic: 8.5 Asian: 29.0 Other: 2.6

29.2 ± 5.8

27.8 ± 1.8

27.7 ± 5.1

FPG > 5.8; or 2 hPG > 10.0; or RPG ≥ 8.9


Khan 1994 [15] Pakistan

1278

4.9

Not reported

26.7 ± 4.6

16 - 20

Not reported

. At least 2 abnormal values: FPG > 5.8; 1 hPG > 10.3; 2 hPG > 7.8/3 hPG > 6.8


Shirazian 2008 [17] Iran

670

12.1

Not reported

NR

24-28

Not reported

At least 2 abnormal values: FPG ≥ 5.5; 1 hPG ≥ 10.0; 2 hPG ≥ 8.3


Sugaya 2000 [18] Japan

416

32.5

Asian

30.3 ± 4.3

25.4 ± 8.2

22.4 ± 3.8

At least 2 abnormal values: FPG ≥ 5.5; 1 hPG ≥ 10.0; 2 hPG ≥ 8.3


GDM: Gestational diabetes; OGTT: Oral glucose tolerance test; PG: Plasma glucose; FPG: Fasting PG; RPG: random PG

1 GDM incidence according to WHO except for Black et al., who used the IASDPG criteria

2 Range or mean ± SD

3 The meta-analyses only included untreated women, as defined in each study

Wendland et al. BMC Pregnancy and Childbirth 2012 12:23   doi:10.1186/1471-2393-12-23

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