Table 2

Associations of childhood and adulthood direct pesticide application with PD in negative history families.

% Exposed*

Cases, n = 228

Controls, n = 215

p for trend (GEE model 1)**

OR and 95% CI (GEE model 2)**

History of pesticide use

Ever

62.7

47.4

1.80

1.20–2.70

Never

37.3

52.6

1.00

Referent

Frequency (days/year)

<0.001

>10

24.1

11.2

2.55

1.38–4.73

4–10

15.8

13.0

1.58

0.84–2.99

<4

19.7

18.6

1.52

0.89–2.62

Never

37.3

52.6

1.00

Referent

Duration (years)

0.012

>25

21.9

13.5

1.98

1.14–3.46

10–25

18.4

18.6

1.32

0.76–2.28

<10

17.5

11.6

2.04

1.08–3.88

Never

37.3

52.6

1.00

Referent

Cumulative exposure (days)

<0.001

>179

21.9

10.7

3.25

1.84–5.73

42–179

18.0

15.3

1.46

0.80–2.68

<42

15.4

14.0

1.48

0.83–2.66

Never

37.3

52.6

1.00

Referent

*Column totals may not sum to 100 due to rounding or missing data.

**GEE model adjusted for AAE, sex, cigarette smoking, and caffeine consumption.

Hancock et al. BMC Neurology 2008 8:6   doi:10.1186/1471-2377-8-6