Table 2

Spearman correlation coefficients comparing mean changes on the ADAS-Cog, CIBIC-Plus, PGAS and CGAS with mean changes on other outcomes at 6 months

ADAS-Cog
ADAS-Cog
ADAS-Cog
improved
 no change
worsened
ADAS-Cog
 CIBIC-Plus
PGAS*
 CGAS*
(n = 19)
 (n = 53)
 (n = 23)
 (n = 95)
 (n = 95)
 (n = 95)
 (n = 95)
CIBIC-Plus
 -0.15
 0.15
 0.38
 0.27
 1.00

PGAS*
 0.40
 -0.32
 -0.15
 -0.09
 -0.59
 1.00
     Cognition*
 0.58
 -0.50
 -0.32
 -0.22
 -0.60
 0.81
 0.58
     Function*
 0.23
 -0.25
 -0.07
 -0.03
 -0.27
 0.69
 0.22
     Behaviour*
 -0.33
 0.17
 -0.17
 -0.06
 -0.12
 0.47
 0.18
     Leisure*
 0.44
 -0.32
 -0.15
 -0.11
 -0.50
 0.87
 0.36
     Social*
 0.73
 -0.32
 -0.50
 -0.04
 -0.52
 0.72
 0.39
CGAS*
 0.33
 -0.09
 -0.32
 -0.22
 -0.77
 0.52
 1.00
     Cognition*
 0.41
 -0.12
 -0.27
 -0.21
 -0.69
 0.51
 0.84
     Function*
 0.36
 -0.29
 0.20
 -0.14
 -0.60
 0.51
 0.77
     Behaviour*
 0.20
 0.35
 -0.43
 -0.30
 -0.72
 0.41
 0.89
     Leisure*
 -1.00
 0.11
 0.29
 0.12
 -0.25
 0.32
 0.63
     Social*
 0.15
 -0.31
 0.21
 0.01
 -0.76
 0.48
 0.86
MMSE*
 0.59
 -0.18
 -0.24
 -0.35
 -0.29
 0.24
 0.32
PSMS
 -0.28
 0.00
 0.37
 0.21
 0.51
 -0.36
 -0.53
IADL
 -0.29
 0.16
 -0.15
 0.11
 0.37
 -0.27
 -0.46
CSD
 0.24
 -0.03
 0.39
 0.25
 0.40
 -0.15
 -0.53

*Higher scores indicate better performance (the expected direction is positive), otherwise lower scores indicate improvement.

Rockwood et al. BMC Neurology 2007 7:26   doi:10.1186/1471-2377-7-26