Table 2

Spearman correlation coefficients comparing mean changes on the ADAS-Cog, CIBIC-Plus, PGAS and CGAS with mean changes on other outcomes at 6 months

ADAS-Cog

ADAS-Cog

ADAS-Cog

improved

no change

worsened

ADAS-Cog

CIBIC-Plus

PGAS*

CGAS*

(n = 19)

(n = 53)

(n = 23)

(n = 95)

(n = 95)

(n = 95)

(n = 95)


CIBIC-Plus

-0.15

0.15

0.38

0.27

1.00

PGAS*

0.40

-0.32

-0.15

-0.09

-0.59

1.00

Cognition*

0.58

-0.50

-0.32

-0.22

-0.60

0.81

0.58

Function*

0.23

-0.25

-0.07

-0.03

-0.27

0.69

0.22

Behaviour*

-0.33

0.17

-0.17

-0.06

-0.12

0.47

0.18

Leisure*

0.44

-0.32

-0.15

-0.11

-0.50

0.87

0.36

Social*

0.73

-0.32

-0.50

-0.04

-0.52

0.72

0.39

CGAS*

0.33

-0.09

-0.32

-0.22

-0.77

0.52

1.00

Cognition*

0.41

-0.12

-0.27

-0.21

-0.69

0.51

0.84

Function*

0.36

-0.29

0.20

-0.14

-0.60

0.51

0.77

Behaviour*

0.20

0.35

-0.43

-0.30

-0.72

0.41

0.89

Leisure*

-1.00

0.11

0.29

0.12

-0.25

0.32

0.63

Social*

0.15

-0.31

0.21

0.01

-0.76

0.48

0.86

MMSE*

0.59

-0.18

-0.24

-0.35

-0.29

0.24

0.32

PSMS

-0.28

0.00

0.37

0.21

0.51

-0.36

-0.53

IADL

-0.29

0.16

-0.15

0.11

0.37

-0.27

-0.46

CSD

0.24

-0.03

0.39

0.25

0.40

-0.15

-0.53


*Higher scores indicate better performance (the expected direction is positive), otherwise lower scores indicate improvement.

Rockwood et al. BMC Neurology 2007 7:26   doi:10.1186/1471-2377-7-26

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