|
Mean [SEM] of plasma hormone concentrations during the baseline and treatment period, and results of neuroendocrinological tests |
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| Baseline period |
Treatment period |
p* |
|
|
|
|||
| Plasma hormone concentrations (means of monthly tests) |
|||
| Prolactin (ng/ml) |
10.2 [0.8]* |
8.7 [0.7]* |
0.027 |
| Cortisol (ng/ml) |
114.4 [23.2] |
122.4 [22.8] |
n.s. |
| ACTH (pg/ml) |
17.4 [2.3] |
19.9 [4.3] |
n.s. |
| DEX-CRH test |
|||
| CORT max (ng/ml) |
39.7 [8] |
41.1 [14] |
n.s. |
| CORT AUC |
147.5 [30] |
152.8 [55] |
n.s. |
| ACTH max (pg/ml) |
20.4 [5] |
22.5 [11] |
n.s. |
| ACTH AUC |
49.4 [7] |
46.6 [11] |
n.s. |
| ACTH test |
|||
| ACTH base (pg/ml) |
24.40 [12.21] |
28.69 [7.23] |
n.s. |
| CORT base (ng/ml) |
175.1 [22.6] |
169.9 [22.4] |
n.s. |
| CORT 60 min (ng/ml) |
330.7 [59] |
275.8 [26.5] |
n.s. |
| Delta Cort (ng/ml) |
149.70 [35.67] |
163.00 [32.40] |
n.s. |
|
* p for comparisons of baseline vs. treatment periods, MANOVA | |||
Then Bergh et al. BMC Neurology 2006 6:19 doi:10.1186/1471-2377-6-19 |
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