Table 2

T2 lesion load and brain fractional volume (Mean [SEM]).


Baseline period
Treatment period


Month 1
Month 6
Change (mth 6 vs. mth 1)
Month 7
Month 12
Change (mth 12 vs. mth 7)
Change (mth 12 vs. mth 6)

T2 lesion load (ml)
19.93 [4.8]
22.49 [4.64]
+ 13 %
p < 0.001
20.68 [4.23]
17.70 [4.17]
- 14 %
p = 0.001
- 21%
p = 0.001
BFV (%)
86.4 [1.4]
86.1 [1.8]
- 0.35 %
n.s.
85.9 [1.9]
83.9 [1.8]
-2.33 %
n.s.
-2.56%
n.s.

Multivariate Wilk's test for T2 lesion load, p = 0.002, and for BFV, p = 0.086; p values given in the table are for univariate F tests.

Then Bergh et al. BMC Neurology 2006 6:19   doi:10.1186/1471-2377-6-19