|
Therapeutic studies of EDBP for PDPH |
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| Author |
Number of patients |
Type of study |
Blinding |
Time window to inclusion |
Follow-up |
Outcome |
Adverse effects |
|
|
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| Safa-Tisseront 2001 [8] |
527 (504 analyzed) |
Therapeutic, prospective, non-randomised, observational |
NA |
4 days (1–53) |
15 days |
75% complete relief, 18% incomplete relief, 7% failure |
Fever in 3 patients |
| Williams 1999 [12] |
55 (7 prophylactic, 41 therapeutic EDBP, 7 conservative treatment) |
Retrospective, non-randomised, observational |
NA |
<1 week |
? |
34% complete relief, 54% incomplete relief, 12% failure |
Back pain in 3 patients |
| Banks 2001 [9] |
100 (81 pdph7 prophylactic, 58 therapeutic EDBP, 23 conservative treatment) |
Prospective, non randomised, observational |
NA |
0–3 days |
? |
67% complete relief, 28% incomplete relief, 5% failure |
22% back pain |
| Taivainen 1993 [7] |
81 (55 patients 10 ml, 26 patients 10–15 ml EDBP) |
Prospective, partly randomised, observational |
NA |
0–10 days |
1 week |
Initial relief 91%, permanent relief 61% |
25% back pain |
| Vercauteren 1999 [11] |
190 (186 EDBP, 4 atypical symptoms) |
Retrospective, non randomised |
NA |
>24 h after symptoms |
1 day |
Initial relief 99%, permanent relief 73% |
? |
| Stride 1993 [10] |
34819 (461 PDPH, 137 EDBP attempted, 135 completed) |
Retrospective, non randomised |
NA |
2 days |
? |
Initial relief 90%, permanent Relief 64% |
? |
| Seebacher 1989 [20] |
12 (6 EDBP, 6 sham treatment) |
Prospective, randomised |
Yes |
>4 days |
1 day |
EDBP 83% relief sham treatment 0% relief |
Back pain |
Oedit et al. BMC Neurology 2005 5:12 doi:10.1186/1471-2377-5-12 |
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