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Open Access Highly Accessed Case report

P-ANCA vasculitic neuropathy with 12-year latency between onset of neuropathy and systemic symptoms

Steven A Greenberg

Author Affiliations

From the Department of Neurology, Division of Neuromuscular Disease, Brigham and Women's Hospital and Harvard Medical School, Boston, USA

BMC Neurology 2002, 2:10  doi:10.1186/1471-2377-2-10

Published: 31 October 2002



The differential diagnosis of chronic progressive multifocal asymmetric neuropathies is challenging. Vasculitic neuropathies, multifocal forms of chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathies, and asymmetric lower motor neuron disorders are important considerations.

Case presentation

We report a patient with an unusually long 12-year course of nonsystemic vasculitic neuropathy prior to the development of systemic manifestations.


We discuss some of the difficulties involved in the diagnosis of chronic progressive multifocal asymmetric neuropathies.

Vasculitic neuropathy; Microscopic polyangiitis; Multifocal neuropathy